Sequencing a Genome: Inside the Washington University Genome Sequencing Center

Take a video tour through the Washington University Genome Sequencing Center. Explore the different labs and offices that make up the preparation, production, and data management facilities. Get a close look at the robotic machines specially designed to handle the high volume of samples. Animated explanations of the processes used to sequence genomic DNA will help you along the way.

The molecular interactions that occur during Sanger cycle sequencing are complex. The animation explains the chemistry behind the dye terminator sequencing reactions used at genome sequencing centers. It will give you a better understanding of the details involved in the synthesis of fluorescently labeled DNA fragments that provide the data for genomic sequencing projects.

More than 150 people work in three areas of employment at the Washington University Genome Sequencing Center — laboratory, informatics, and administration. It takes people with different skills and diverse educational backgrounds to keep the center working efficiently. In this section, meet some of these employees and hear them describe their jobs and their educational backgrounds. Learn about the challenges they face each day and what gives them a sense of satisfaction with their work.